구소 (203.♡.186.18)
2025년 9월 23일 AM 10:43 · 수정됨(11:16)
아무래도 트럼프 자문 역할 중 누군가가 이 연구 이야기를 한 것 같습니다.
결론이 이렇거든요: Our analyses using the Navigation Guide thus support evidence consistent with an association between acetaminophen exposure during pregnancy and increased incidence of NDDs. Appropriate and immediate steps should be taken to advise pregnant women to limit acetaminophen consumption to protect their offspring’s neurodevelopment.
반박의 여지가 많은 연구이고, 주의 하는 것이 좋을 것 같습니다.
Evaluation of the evidence on acetaminophen use and neurodevelopmental disorders using the Navigation Guide methodology
Background
Acetaminophen is the most commonly used over-the-counter pain and fever medication taken during pregnancy, with > 50% of pregnant women using acetaminophen worldwide. Numerous well-designed studies have indicated that pregnant mothers exposed to acetaminophen have children diagnosed with neurodevelopmental disorders (NDDs), including autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD), at higher rates than children of pregnant mothers who were not exposed to acetaminophen.
Methods
We applied the Navigation Guide methodology to the scientific literature to comprehensively and objectively examine the association between prenatal acetaminophen exposure and NDDs and related symptomology in offspring. We conducted a systematic PubMed search through February 25, 2025, using predefined inclusion criteria and rated studies based on risk of bias and strength of evidence. Due to substantial heterogeneity, we opted for a qualitative synthesis, consistent with the Navigation Guide’s focus on environmental health evidence.
Results
We identified 46 studies for inclusion in our analysis. Of these, 27 studies reported positive associations (significant links to NDDs), 9 showed null associations (no significant link), and 4 indicated negative associations (protective effects). Higher-quality studies were more likely to show positive associations. Overall, the majority of the studies reported positive associations of prenatal acetaminophen use with ADHD, ASD, or NDDs in offspring, with risk-of-bias and strength-of-evidence ratings informing the overall synthesis.
Conclusions
Our analyses using the Navigation Guide thus support evidence consistent with an association between acetaminophen exposure during pregnancy and increased incidence of NDDs. Appropriate and immediate steps should be taken to advise pregnant women to limit acetaminophen consumption to protect their offspring’s neurodevelopment.
댓글 (3)
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Aawful
25.09.23 · 118.♡.15.202
보건부 장관이 오랫동안 백신이 자폐 원인이라 주장해 왔으니 곧 백신이 위험하다며 백신 접종도 막을 것 같습니다 -
PPhysicist
25.09.23 · 66.♡.205.125
https://www.nbcnews.com/health/health-news/trump-acetaminophen-fda-pregnancy-autism-cause-rcna232909
Outside autism researchers, however, said that the review wasn’t rigorously conducted and that it cherry-picked studies that supported its conclusion. 외부 자폐증 연구자들은 이 연구가 엄격하게 진행되지 않았으며, 자신들의 결론을 뒷받침하는 연구들만 선별(cherry-pick)했다고 말했습니다.
The review’s senior author, Dr. Andrea Baccarelli, served in 2023 as a paid expert in a class action lawsuit against acetaminophen manufacturers, in which he testified that there was a link between the medication and autism. A judge ultimately excluded his testimony for being scientifically unsound and last year dismissed the case, which is being appealed. 해당 연구의 선임 저자인 안드레아 바카렐리 박사는 2023년에 아세트아미노펜 제조업체들을 상대로 한 집단 소송에서 유료 전문가로 활동하며, 이 약물과 자폐증 사이의 연관성이 있다고 증언했습니다. 그러나 한 판사는 그의 증언이 과학적으로 근거가 없다고 판단하여 최종적으로 증언을 배제했고, 지난해 해당 소송은 기각되었으며 현재 항소 진행 중입니다.
https://thehill.com/policy/healthcare/5515722-tylenol-autism-link-white-house/
However, experts say the study was flawed, did not show causation and was not sufficient grounds for changing medical recommendations. 하지만 전문가들은 해당 연구에 결함이 있고, 인과관계를 입증하지 못했으며, 의료 권고를 변경할 충분한 근거가 되지 못한다고 말합니다.
Diddier Prada, a researcher at Icahn School of Medicine at Mount Sinai, which led the study, stressed that the findings do not prove a causal link. 연구를 주도한 마운트 시나이 아이칸 의과대학의 연구원인 디디에 프라다(Diddier Prada)는 이번 연구 결과가 인과관계를 증명하는 것은 아니라고 강조했습니다.
“We show that acetaminophen is associated with a higher risk, but not causing it. Those are very different things,” he said in an interview with The Washington Post. 그는 워싱턴포스트와의 인터뷰에서 "우리는 아세트아미노펜이 더 높은 위험과 관련이 있다는 것을 보여줄 뿐, 원인을 제공한다는 것은 아닙니다. 이 둘은 매우 다른 것입니다"라고 말했습니다.
위의 연구 결과를 받아드리고 이해하는 것은 개개인의 신념과 생각에 달려있지만 이미 많은 매체에서 다룬 내용이고 오늘자 기사에도 많이 다시 재 확인하고 있습니다. -
구구소
→ Physicist 작성자
25.09.23 · 203.♡.186.18
네, 저도 확인 한 내용입니다. 일반적으로 연구 논문에서 저렇게 강한 어조를 쓰지 않거근요..그래서 링크를 첨부하고 논문을 직접 보는게 좋다는 의미로 게시한 것입니다.
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